{"id":2451,"date":"2026-03-09T11:07:32","date_gmt":"2026-03-09T08:07:32","guid":{"rendered":"https:\/\/www.esteperapoliklinik.com\/en\/?p=2451"},"modified":"2026-03-09T11:07:32","modified_gmt":"2026-03-09T08:07:32","slug":"what-is-mesotherapy-how-is-it-used-in-skin-rejuvenation","status":"publish","type":"post","link":"https:\/\/www.esteperapoliklinik.com\/en\/what-is-mesotherapy-how-is-it-used-in-skin-rejuvenation\/","title":{"rendered":"What Is Mesotherapy? How Is It Used in Skin Rejuvenation?"},"content":{"rendered":"<p>Mesotherapy is a medical aesthetic procedure based on the principle of delivering active substances such as vitamins, minerals, amino acids, and hyaluronic acid into the skin via micro-injections. This method, which has been used in dermatology and aesthetic medicine for many years, is particularly preferred to improve skin quality and reduce signs of aging.<\/p>\n<p>As we age, collagen production in the skin decreases, loss of elasticity occurs, and the skin may take on a duller appearance. Mesotherapy treatments aim to support this process by delivering the active substances the skin needs directly to the dermis layer. This can help achieve a more vibrant, radiant, and healthier-looking skin.<\/p>\n<p>At Estepera Polyclinic, mesotherapy treatments are planned by evaluating the individual&#8217;s skin structure and needs. The procedure is considered not only as an aesthetic treatment but also as a medical approach that supports skin quality.<\/p>\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_71 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Table of Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 eztoc-toggle-hide-by-default' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/www.esteperapoliklinik.com\/en\/what-is-mesotherapy-how-is-it-used-in-skin-rejuvenation\/#What_Is_Mesotherapy\" title=\"What Is Mesotherapy?\">What Is Mesotherapy?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/www.esteperapoliklinik.com\/en\/what-is-mesotherapy-how-is-it-used-in-skin-rejuvenation\/#How_Does_Mesotherapy_Affect_the_Skin\" title=\"How Does Mesotherapy Affect the Skin?\">How Does Mesotherapy Affect the Skin?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/www.esteperapoliklinik.com\/en\/what-is-mesotherapy-how-is-it-used-in-skin-rejuvenation\/#How_Is_Mesotherapy_Used_in_Skin_Rejuvenation\" title=\"How Is Mesotherapy Used in Skin Rejuvenation?\">How Is Mesotherapy Used in Skin Rejuvenation?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/www.esteperapoliklinik.com\/en\/what-is-mesotherapy-how-is-it-used-in-skin-rejuvenation\/#For_Which_Skin_Concerns_Is_Mesotherapy_Suitable\" title=\"For Which Skin Concerns Is Mesotherapy Suitable?\">For Which Skin Concerns Is Mesotherapy Suitable?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/www.esteperapoliklinik.com\/en\/what-is-mesotherapy-how-is-it-used-in-skin-rejuvenation\/#How_Is_Mesotherapy_Applied\" title=\"How Is Mesotherapy Applied?\">How Is Mesotherapy Applied?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/www.esteperapoliklinik.com\/en\/what-is-mesotherapy-how-is-it-used-in-skin-rejuvenation\/#What_Happens_to_the_Skin_After_Mesotherapy\" title=\"What Happens to the Skin After Mesotherapy?\">What Happens to the Skin After Mesotherapy?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/www.esteperapoliklinik.com\/en\/what-is-mesotherapy-how-is-it-used-in-skin-rejuvenation\/#Who_Is_a_Suitable_Candidate_for_Mesotherapy\" title=\"Who Is a Suitable Candidate for Mesotherapy?\">Who Is a Suitable Candidate for Mesotherapy?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/www.esteperapoliklinik.com\/en\/what-is-mesotherapy-how-is-it-used-in-skin-rejuvenation\/#Frequently_Asked_Questions_FAQ\" title=\"Frequently Asked Questions (FAQ)\">Frequently Asked Questions (FAQ)<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/www.esteperapoliklinik.com\/en\/what-is-mesotherapy-how-is-it-used-in-skin-rejuvenation\/#1_Is_mesotherapy_really_effective_in_skin_rejuvenation\" title=\"1. Is mesotherapy really effective in skin rejuvenation?\">1. Is mesotherapy really effective in skin rejuvenation?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/www.esteperapoliklinik.com\/en\/what-is-mesotherapy-how-is-it-used-in-skin-rejuvenation\/#2_How_many_sessions_of_mesotherapy_are_applied\" title=\"2. How many sessions of mesotherapy are applied?\">2. How many sessions of mesotherapy are applied?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-11\" href=\"https:\/\/www.esteperapoliklinik.com\/en\/what-is-mesotherapy-how-is-it-used-in-skin-rejuvenation\/#3_Is_the_mesotherapy_procedure_painful\" title=\"3. Is the mesotherapy procedure painful?\">3. Is the mesotherapy procedure painful?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-12\" href=\"https:\/\/www.esteperapoliklinik.com\/en\/what-is-mesotherapy-how-is-it-used-in-skin-rejuvenation\/#4_When_can_one_return_to_daily_life_after_mesotherapy\" title=\"4. When can one return to daily life after mesotherapy?\">4. When can one return to daily life after mesotherapy?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-13\" href=\"https:\/\/www.esteperapoliklinik.com\/en\/what-is-mesotherapy-how-is-it-used-in-skin-rejuvenation\/#5_Can_mesotherapy_be_combined_with_other_skin_rejuvenation_treatments\" title=\"5. Can mesotherapy be combined with other skin rejuvenation treatments?\">5. Can mesotherapy be combined with other skin rejuvenation treatments?<\/a><\/li><\/ul><\/li><\/ul><\/nav><\/div>\n<h2><span class=\"ez-toc-section\" id=\"What_Is_Mesotherapy\"><\/span>What Is Mesotherapy?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><a href=\"https:\/\/www.esteperapoliklinik.com\/en\/mesotherapy\/\">Mesotherapy<\/a> takes its name from the &#8220;mesoderm,&#8221; the middle layer of the skin. In this method, specially formulated mixtures are applied beneath the skin using very fine needles. The goal is to support cellular renewal in the skin and improve skin quality.<\/p>\n<p>The substances delivered to the skin may help stimulate fibroblast cells to support collagen and elastin production. This plays an important role particularly in reducing the appearance of fine wrinkles and supporting skin elasticity.<\/p>\n<p>The ingredients used in mesotherapy treatments generally include the following components:<\/p>\n<ul>\n<li>Hyaluronic acid<\/li>\n<li>Vitamin complexes<\/li>\n<li>Amino acids<\/li>\n<li>Antioxidants<\/li>\n<li>Minerals<\/li>\n<\/ul>\n<p>These ingredients can be prepared in different combinations according to the skin&#8217;s needs.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"How_Does_Mesotherapy_Affect_the_Skin\"><\/span>How Does Mesotherapy Affect the Skin?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Skin aging is associated with collagen loss, decreased elasticity, and slowed cellular renewal. Mesotherapy treatment aims to support this process through active ingredients delivered beneath the skin.<\/p>\n<p>Thanks to the micro-injection technique, the ingredients reach the dermis layer directly. This allows for a more targeted effect compared to creams applied on the surface of the skin.<\/p>\n<p>The main effects of mesotherapy on the skin are as follows:<\/p>\n<ul>\n<li>May help increase moisture levels in the skin<\/li>\n<li>May support collagen production<\/li>\n<li>May contribute to a more even skin tone<\/li>\n<li>May help reduce the appearance of fine lines and wrinkles<\/li>\n<li>May create a more vibrant and radiant appearance in the skin<\/li>\n<\/ul>\n<p>These effects may vary from person to person, and the treatment plan is determined through individual assessment.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"How_Is_Mesotherapy_Used_in_Skin_Rejuvenation\"><\/span>How Is Mesotherapy Used in Skin Rejuvenation?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>In skin rejuvenation treatments, mesotherapy is generally planned as a course of sessions. The intervals between sessions and the number of sessions may vary depending on the individual&#8217;s skin type, age, and expectations.<\/p>\n<p>Mesotherapy can often be applied on its own or planned in combination with other medical aesthetic treatments. Especially when combined with collagen-stimulating technologies such as <a href=\"https:\/\/www.esteperapoliklinik.com\/en\/gold-needle-skin-rejuvenation-and-renewal\/\">Gold Needle<\/a> or <a href=\"https:\/\/www.esteperapoliklinik.com\/en\/morpheus-8\/\">Morpheus 8<\/a>, it may help support the skin renewal process.<\/p>\n<p>Additionally, protocols planned in combination with treatments such as <a href=\"https:\/\/www.esteperapoliklinik.com\/en\/hydrafacial\/\">Hydrafacial<\/a>, which provide skin cleansing and barrier support, can make the skin care process more holistic.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"For_Which_Skin_Concerns_Is_Mesotherapy_Suitable\"><\/span>For Which Skin Concerns Is Mesotherapy Suitable?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Mesotherapy treatments can be used not only for signs of aging but also to support various skin problems.<\/p>\n<p>The most common conditions for which it is preferred are:<\/p>\n<ul>\n<li>Skin moisture loss<\/li>\n<li>Dull and tired appearance<\/li>\n<li>Fine wrinkles<\/li>\n<li>Loss of elasticity<\/li>\n<li>Uneven skin tone<\/li>\n<li>Sun damage<\/li>\n<\/ul>\n<p>In some cases, mesotherapy can also be planned as a supportive method in <a href=\"https:\/\/www.esteperapoliklinik.com\/en\/spot-treatment\/\">spot treatment<\/a> processes.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"How_Is_Mesotherapy_Applied\"><\/span>How Is Mesotherapy Applied?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Prior to the application, the individual&#8217;s skin structure is evaluated and the content to be used is determined. The skin is then cleansed and, if necessary, a topical anesthetic cream may be applied.<\/p>\n<p>The mesotherapy procedure is generally completed in a short time, and special ingredients are delivered beneath the skin using the micro-injection technique.<\/p>\n<p>The application process generally consists of the following steps:<\/p>\n<ul>\n<li>Skin analysis<\/li>\n<li>Selection of appropriate ingredients<\/li>\n<li>Cleansing of the skin<\/li>\n<li>Micro-injection application<\/li>\n<li>Post-procedure care recommendations<\/li>\n<\/ul>\n<p>The application time is generally short, and in most cases the individual can return to daily life quickly.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"What_Happens_to_the_Skin_After_Mesotherapy\"><\/span>What Happens to the Skin After Mesotherapy?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>After mesotherapy, mild redness or sensitivity may be observed on the skin. This condition generally subsides within a short time.<\/p>\n<p>The following changes may be observed on the skin after the procedure:<\/p>\n<ul>\n<li>A more vibrant appearance<\/li>\n<li>Increased skin moisture<\/li>\n<li>Improvement in skin tone<\/li>\n<li>Reduction in the appearance of fine lines<\/li>\n<\/ul>\n<p>Results generally become more noticeable after several sessions.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Who_Is_a_Suitable_Candidate_for_Mesotherapy\"><\/span>Who Is a Suitable Candidate for Mesotherapy?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Mesotherapy treatments may be a suitable option generally for individuals who want to improve their skin quality. However, as with any medical procedure, personal evaluation is important.<\/p>\n<p>Suitable candidates for mesotherapy are generally:<\/p>\n<ul>\n<li>Those experiencing skin moisture loss<\/li>\n<li>Those with complaints of fine wrinkles<\/li>\n<li>Those who want to support their skin quality<\/li>\n<li>Those who complain of a dull and tired skin appearance<\/li>\n<\/ul>\n<p>The treatment plan should be created on an individual basis following a dermatological evaluation.<\/p>\n<p><iframe loading=\"lazy\" title=\"YouTube video player\" src=\"https:\/\/www.youtube.com\/embed\/cGslMQubMao?si=3pBjPDz5jD0Ze8gw\" width=\"100%\" height=\"600\" frameborder=\"0\" allowfullscreen=\"allowfullscreen\"><span data-mce-type=\"bookmark\" style=\"display: inline-block; width: 0px; overflow: hidden; line-height: 0;\" class=\"mce_SELRES_start\">\ufeff<\/span><\/iframe><\/p>\n<h2><span class=\"ez-toc-section\" id=\"Frequently_Asked_Questions_FAQ\"><\/span>Frequently Asked Questions (FAQ)<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<h3><span class=\"ez-toc-section\" id=\"1_Is_mesotherapy_really_effective_in_skin_rejuvenation\"><\/span>1. Is mesotherapy really effective in skin rejuvenation?<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>Mesotherapy is a treatment that aims to support skin quality through active ingredients such as vitamins, amino acids, and hyaluronic acid delivered beneath the skin. It may help support collagen production and contribute to a more vibrant, more hydrated, and healthier-looking skin.<\/p>\n<h3><span class=\"ez-toc-section\" id=\"2_How_many_sessions_of_mesotherapy_are_applied\"><\/span>2. How many sessions of mesotherapy are applied?<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>Mesotherapy treatments are generally planned as a course of sessions. The number of sessions may vary depending on the individual&#8217;s skin type, age, and needs. In most cases, several sessions at specific intervals may be recommended.<\/p>\n<h3><span class=\"ez-toc-section\" id=\"3_Is_the_mesotherapy_procedure_painful\"><\/span>3. Is the mesotherapy procedure painful?<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>Since very fine needles are used during mesotherapy, the procedure is generally tolerable. When deemed necessary, an anesthetic cream can be applied before the procedure to enhance comfort.<\/p>\n<h3><span class=\"ez-toc-section\" id=\"4_When_can_one_return_to_daily_life_after_mesotherapy\"><\/span>4. When can one return to daily life after mesotherapy?<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>Most people can return to their daily routine on the same day after mesotherapy. Mild redness or sensitivity may occur on the skin after the procedure, but this generally subsides within a short time.<\/p>\n<h3><span class=\"ez-toc-section\" id=\"5_Can_mesotherapy_be_combined_with_other_skin_rejuvenation_treatments\"><\/span>5. Can mesotherapy be combined with other skin rejuvenation treatments?<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>Yes, in some cases mesotherapy can be planned in combination with other medical aesthetic treatments. In skin rejuvenation protocols, it can be combined with treatments such as Hydrafacial, Gold Needle, or Morpheus 8. The most suitable plan should be determined through expert evaluation.<\/p>\n<p><strong>For Detailed Information and <a href=\"https:\/\/www.esteperapoliklinik.com\/en\/contact\/\">Questions<\/a>, You Can Reach Us via <a href=\"https:\/\/api.whatsapp.com\/send?phone=905304014999&amp;text=Hello, I am reaching you from your website, may I get information?\" target=\"_blank\" rel=\"noopener\">WhatsApp<\/a>. You Can Also Follow Us on Our <a href=\"https:\/\/www.instagram.com\/esteperapoliklinik\/\" target=\"_blank\" rel=\"noopener\">Instagram<\/a> Address.<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Mesotherapy is a medical aesthetic procedure based on the principle of delivering active substances such as vitamins, minerals, amino acids, and hyaluronic acid into the skin via micro-injections. This method, which has been used in dermatology and aesthetic medicine for many years, is particularly preferred to improve skin quality and reduce signs of aging. As [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":2452,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[19],"tags":[],"_links":{"self":[{"href":"https:\/\/www.esteperapoliklinik.com\/en\/wp-json\/wp\/v2\/posts\/2451"}],"collection":[{"href":"https:\/\/www.esteperapoliklinik.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.esteperapoliklinik.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.esteperapoliklinik.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.esteperapoliklinik.com\/en\/wp-json\/wp\/v2\/comments?post=2451"}],"version-history":[{"count":2,"href":"https:\/\/www.esteperapoliklinik.com\/en\/wp-json\/wp\/v2\/posts\/2451\/revisions"}],"predecessor-version":[{"id":2454,"href":"https:\/\/www.esteperapoliklinik.com\/en\/wp-json\/wp\/v2\/posts\/2451\/revisions\/2454"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.esteperapoliklinik.com\/en\/wp-json\/wp\/v2\/media\/2452"}],"wp:attachment":[{"href":"https:\/\/www.esteperapoliklinik.com\/en\/wp-json\/wp\/v2\/media?parent=2451"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.esteperapoliklinik.com\/en\/wp-json\/wp\/v2\/categories?post=2451"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.esteperapoliklinik.com\/en\/wp-json\/wp\/v2\/tags?post=2451"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}